SALL4 Expression in Gastrointestinal and Pancreatic Adenocarcinoma and Hepatocellular Carcinoma: An Immunohistochemical Study

The Relationship between Cytokeratins 7 and 20 Expression, and Prognostic Factors in Colon Adenocarcinoma: An Immunohistochemical Study

Background & Objective: The role of synchronized expression pattern of cytokeratin (CK) 7 and CK20 in the prognosis of colon adenocarcinoma is unclear. The current study aimed at determining the relationship between the expression of cytokeratins 7 and 20 and prognostic factors in colon adenocarcinoma. Methods: In the current cr...

Oncofetal gene SALL4 in aggressive hepatocellular carcinoma.

BACKGROUND Hepatocellular carcinoma is the third leading cause of cancer-related deaths worldwide. In the heterogeneous group of hepatocellular carcinomas, those with characteristics of embryonic stem-cell and progenitor-cell gene expression are associated with the worst prognosis. The oncofetal gene SALL4, a marker of a subtype of hepatocellular carcinoma with progenitor-like features, is asso...

Oncofetal Gene SALL4 in Aggressive Hepatocellular Carcinoma

Kol Jia Yong, B.Sc., Chong Gao, M.D., Ph.D., Joline S.J. Lim, M.B., B.S., Benedict Yan, M.B., B.S., Henry Yang, Ph.D., Todor Dimitrov, Ph.D., Akira Kawasaki, M.D., Ph.D., Chee Wee Ong, M.Sc., Kwong-Fai Wong, Ph.D., Sanghoon Lee, Ph.D., Sharada Ravikumar, M.D., Ph.D., Supriya Srivastava, M.D., Xi Tian, B.S., Ronnie T. Poon, M.B., B.S., Ph.D., Sheung Tat Fan, M.D., D.Sc., John M. Luk, D.Med.Sc., ...

The expression and functions of microRNAs in pancreatic adenocarcinoma and hepatocellular carcinoma

Pancreatic adenocarcinoma and hepatocellular carcinoma are devastating human malignancies that are characterized by poor prognosis, late onset, and a lack of known biomarkers. New diagnostic and therapeutic molecular targets are desperately needed to develop novel and effective treatment strategies. MicroRNAs (miRNAs) are an emerging class of molecules with roles in various cellular processes, ...

Angiogenesis in Pancreatic Ductal Adenocarcinoma: Morphometric and Immunohistochemical Study